How does it work?
Eszopiclone is part of the non-benzodiazepine hypnotic class of medications. It works by interacting with GABA-A receptors in the brain, enhancing the effects of gamma-aminobutyric acid (GABA), a neurotransmitter that promotes relaxation and reduces brain activity. This modulation has a calming effect, facilitating faster sleep onset and sustaining sleep throughout the night.
Key points in the mechanism of action include:
GABA Enhancement: Eszopiclone binds to specific GABA receptors in the brain, leading to sedative effects that promote sleep.
Sleep Maintenance helps individuals fall asleep faster and maintain sleep for more extended periods, thus reducing nighttime awakenings.
Minimal Impact on Sleep Architecture: Unlike other sedatives, Eszopiclone has minimal disruption to the natural sleep cycle (sleep architecture), meaning the different stages of sleep, including deep sleep and REM (rapid eye movement), remain mostly intact.
Uses of Eszopiclone 2 mg (Hypnite-2)
The primary therapeutic use of Eszopiclone 2 mg is for the treatment of insomnia. Insomnia can vary in its presentation, and Eszopiclone is effective in treating multiple forms of this condition, including:
Sleep-onset insomnia: Difficulty falling asleep at the beginning of the night.
Sleep maintenance insomnia is waking up frequently during the night or too early in the morning and having trouble going back to sleep.
Eszopiclone is often used when behavioural interventions or other treatment methods have not provided sufficient relief. It is particularly beneficial for:
Chronic insomnia: For individuals experiencing prolonged and persistent difficulties with sleep.
Transient insomnia: Temporary insomnia caused by situational stress, anxiety, or other short-term factors.
In some instances, Hypnite-2 may be prescribed to address insomnia associated with other conditions, such as:
- Shift work sleep disorder: For people who work irregular hours and have trouble sleeping during the day.
- Jet lag: Helping travellers adjust to new time zones by regulating their sleep cycle.
- Stress-related insomnia: Eszopiclone is used in patients experiencing sleep difficulties due to anxiety or emotional stress.
Dosage and Administration
The recommended dose of Eszopiclone 2 mg (Hypnite-2) is typically taken once daily, immediately before bed. The tablet should be taken orally, and it is important not to crush or chew the pill, as this can affect the medication’s release into the bloodstream.
Dosage guidelines include:
Timing: Eszopiclone should only be taken when the patient can dedicate 7-8 hours to sleep, as taking it without sufficient time for rest can result in next-day drowsiness.
On an empty stomach: For faster absorption, it is recommended to take Hypnite-2 on an empty stomach or at least avoid taking it immediately after a heavy meal, as food can slow down the Medicine’s absorption.
Potential Side Effects
While Eszopiclone 2 mg is effective in treating insomnia, it can have side effects in some individuals. The most common side effects include:
Drowsiness the next day: Some people may experience residual or grogginess, especially if they do not sleep for 7-8 hours.
Unpleasant taste in the mouth: Many patients report a metallic or bitter taste after taking Eszopiclone.
Dizziness or lightheadedness: These symptoms may be more pronounced when standing up suddenly.
Behavioural changes: In some rare cases, mood swings, irritability, or hallucinations.
In rare instances, individuals may engage in activities like driving, making phone calls, or preparing food without being fully awake and have no recollection of these events afterwards. These complex behaviours require immediate discontinuation of the medicine and consultation with a healthcare provider.
Precautions and Warnings
Eszopiclone 2 mg comes with several important precautions, particularly concerning its soothing effects and the potential for dependence. Some of the critical considerations are:
Avoid Alcohol: Mixing alcohol with Eszopiclone can heighten the sedative effects, leading to extreme drowsiness, impaired motor skills, and even dangerous outcomes such as respiratory depression.
Potential for Abuse and Dependence: Long-term use of Hypnite-2 may lead to tolerance, meaning the same dose becomes less effective over time. This can result in dependency, and individuals may find it difficult to stop using the medicine without experiencing withdrawal symptoms.
Daytime Drowsiness: Even though Hypnite-2 is taken at night, some patients may feel groggy the following day, mainly if they do not sleep a whole night. This can impair activities requiring alertness, such as driving or operating heavy machinery.
Use in Elderly Patients: Older adults are more sensitive to the sedative effects of Eszopiclone and are at higher risk of falls, cognitive impairment, and motor coordination issues.
Pregnancy and Breastfeeding: Eszopiclone should only be used during pregnancy if necessary. Its effects on breastfeeding are not fully understood, and caution is advised.
Medicine Interactions
Eszopiclone can interact with several other medications, which may alter its effects or increase the risk of side effects. Common interactions include:
CNS Depressants: Medications that suppress the central nervous system, such as opioids, antipsychotics, and certain antihistamines, can amplify the sedative effects of Eszopiclone.
CYP3A4 Inhibitors: Medicines like ketoconazole, erythromycin, or grapefruit juice can increase the blood levels of Eszopiclone, leading to more pronounced effects or increased side effects.
Antidepressants: Some antidepressants (SSRIs, for instance) may heighten the sedative effects of Eszopiclone or increase the risk of complex behaviours like sleepwalking.
Patients must inform their doctor about all other medications or supplements to avoid harmful interactions.
Dependency and Withdrawal
Eszopiclone, like other sedative-hypnotics, has the potential for dependence if used for long periods. Prolonged use can lead to tolerance, requiring higher doses to achieve the same effect. When the medication is stopped suddenly, withdrawal symptoms such as anxiety, irritability, and rebound insomnia (worsening of insomnia symptoms) may occur.
To avoid withdrawal effects, it is recommended to gradually taper the dose under medical supervision instead of abruptly discontinuing the medication.
FAQs About Eszopiclone 2 mg (Hypnite-2)
How often can I take Zopiclone?
Zopiclone should be taken once per night before bedtime, not to exceed the recommended duration.
What is the typical dosage of Zopiclone?
The standard dosage for adults is 7.5 mg, taken just before bedtime. A lower dose of 3.75 mg may be recommended for elderly patients or those with liver issues.
How long does it take to deliver Eszopiclone 2 mg to the US?
International shipping of Eszopiclone 2 mg to the US takes approximately 14 to 25 days. For domestic shipping, the estimated delivery time is up to 10 days.
Do I need a prescription to buy Eszopiclone 2 mg?
While we offer the option to buy Eszopiclone 2 mg without a prescription internationally, we strongly recommend consulting your physician and seeking medical advice before taking any medication.
Important Note:
Purchasing Eszopiclone 2 mg (Hypnite-2) online from USA-PharmaStore is simple and secure for US customers. It accepts trusted payment methods like Visa, Mastercard, and PayPal, which protect transactions and keep information safe. Customers benefit from guaranteed delivery, with a full refund offered if orders do not arrive as expected, fostering trust in online medication purchases. Responsive customer support is available via email at [email protected], typically responding within 48 hours to any medication or order status questions.
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